The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2025

Filed:

Jan. 29, 2020
Applicant:

Foghorn Therapeutics Inc., Cambridge, MA (US);

Inventors:

Neville John Anthony, Northborough, MA (US);

Rishi G. Vaswani, Lexington, MA (US);

David Simon Millan, Stow, MA (US);

Shawn E. R. Schiller, Haverhill, MA (US);

Assignee:

FOGHORN THERAPEUTICS INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); A61P 35/00 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); A61P 35/00 (2018.01); C07D 471/04 (2013.01);
Abstract

The compounds disclosed herein may be inhibitors of BRG1 (Brahma-related gene-1) and/or BRM (Brahma). The compounds or pharmaceutically acceptable salts thereof are useful for the treatment of disorders associated with an alteration in a BAF complex, e.g., a disorder associated with an alteration in one or both of the BRG1 and BRM proteins. Also disclosed are pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and methods of their preparation and use.


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