The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2025
Filed:
Mar. 15, 2021
Applicants:
Tyk Medicines (Zhengzhou), Inc., Henan, CN;
Tyk Medicines, Inc., Zhejiang, CN;
Inventors:
Jun Li, Henan, CN;
Chengshan Niu, Henan, CN;
Apeng Liang, Henan, CN;
Zhongwei Guo, Henan, CN;
Yusheng Wu, Henan, CN;
Assignees:
TYK MEDICINES (ZHENGZHOU), INC., Henan, CN;
TYK MEDICINES, INC., Zhejiang, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01);
Abstract
A kinase inhibitor compound of formula I or a pharmaceutically acceptable salt, solvate, or prodrug thereof. The compound has good inhibitory activity on EGFR and Her2 exon 20 insertion mutation, EGFR exon 19 deletion and L858R point mutation of exon 21.