The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2025

Filed:

Feb. 16, 2021
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Matthew D. Shair, Lexington, MA (US);

Daniel E. Jeffries, Lexington, MA (US);

Hanna Tukachinsky, Lexington, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 239/42 (2006.01); A61K 45/06 (2006.01); A61P 35/04 (2006.01); C07D 213/82 (2006.01);
U.S. Cl.
CPC ...
C07D 239/42 (2013.01); A61K 45/06 (2013.01); A61P 35/04 (2018.01); C07D 213/82 (2013.01);
Abstract

Disclosed are compounds and pharmaceutically acceptable salts thereof, which are useful as inhibitors nicotinamide N-methyltransferase (NNIMT). Also disclosed are pharmaceutical compositions comprising a compound disclosed herein. Related methods of treating cancer in a subject and methods of inhibiting tumor growth in subject are also disclosed.


Find Patent Forward Citations

Shair, Matthew. (2025). Inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof (U.S. Patent No. 12509430). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12509430

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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