The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2025

Filed:

Oct. 29, 2020
Applicants:

National University Corporation Kumamoto University, Kumamoto, JP;

National University Corporation Tokyo Medical and Dental University, Tokyo, JP;

Japan As Represented BY Director-general of National Institute of Infectious Diseases, Tokyo, JP;

Inventors:

Shuzo Matsushita, Kumamoto, JP;

Kazuhisa Yoshimura, Kumamoto, JP;

Hirokazu Tamamura, Tokyo, JP;

Ami Masuda, Tokyo, JP;

Kohei Takahashi, Tokyo, JP;

Takuya Kobayakawa, Tokyo, JP;

Shigeyoshi Harada, Tokyo, JP;

Tomoyuki Miura, Kyoto, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/438 (2006.01); A61K 39/42 (2006.01); C07D 221/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/438 (2013.01); A61K 39/42 (2013.01); C07D 221/20 (2013.01);
Abstract

CD4 mimic compounds having improved efficacy for anti-HIV treatment and more improved pharmacokinetics are provided. The compounds are represented by formula (I): wherein Ris CH(OCH)—OCHor CH; Ris O or NH; n is 3 to 25; and m is 4 to 22, or a salt thereof. HIV infection inhibitor compositions including the compound or a salt thereof as an active ingredient are also disclosed.


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