The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2025
Filed:
Oct. 30, 2019
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
John T. Wilson, Nashville, TN (US);
Daniel Shae, Nashville, TN (US);
Dinh Chuong Nguyen, Ho Chi Minh, VN;
Assignee:
Vanderbilt University, Nashville, TN (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); C08F 290/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5026 (2013.01); C08F 290/062 (2013.01); C08F 2438/03 (2013.01);
Abstract
A graft copolymer and a method of delivering an active agent to a subject are provided. The graft copolymer includes a polymer backbone, a hydrophilic segment grafted to the polymer backbone, a pH-responsive segment grafted to the polymer backbone, and an endosomal disruption segment grafted to the polymer backbone. The method of delivering an active agent to a subject includes encapsulating the active agent with the graft copolymer and administering the encapsulated active agent to the subject.