The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 30, 2025
Filed:
May. 23, 2022
Applicant:
Beijing Tricisionbio Therapeutics Inc., Beijing, CN;
Inventors:
Yaoxin Lin, Beijing, CN;
Chengqiang Gao, Beijing, CN;
Shiyou Li, Beijing, CN;
Hao Wang, Beijing, CN;
Lei Wu, Beijing, CN;
Qi Xin, Beijing, CN;
Assignee:
BEIJING TRICISIONBIO THERAPEUTICS INC., Beijing, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/1271 (2025.01); A61K 9/51 (2006.01); C07C 213/04 (2006.01); C07C 215/24 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 9/5123 (2013.01); C07C 213/04 (2013.01); C07C 215/24 (2013.01);
Abstract
Provided are an ionizable lipid compound with an adjacent cis-double bond structure, a preparation method therefor, and the use thereof in the delivery of an active therapeutic agent (e.g., a nucleic acid). The ionizable lipid compound can provide a higher encapsulation rate of active substances and a better cell or in vivo transfection rate, and is particularly suitable for preparing nanoparticles with a solid structure.