The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2025

Filed:

Apr. 10, 2020
Applicants:

Hq Medical Netherlands B.v., Rotterdam, NL;

Publiekrechtelijk Rechtspersoon Academisch Ziekenhuis Leiden H.o.d.n. Lumc, Leiden, NL;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); A61K 31/352 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); C07D 209/24 (2006.01); C07D 498/14 (2006.01); C07D 498/22 (2006.01); C07K 14/435 (2006.01); G01N 33/50 (2006.01); G01N 33/533 (2006.01); G01N 33/574 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56966 (2013.01); A61K 31/352 (2013.01); A61K 31/403 (2013.01); A61K 31/404 (2013.01); C07D 209/24 (2013.01); C07D 498/14 (2013.01); C07D 498/22 (2013.01); C07K 14/435 (2013.01); G01N 33/5008 (2013.01); G01N 33/5091 (2013.01); G01N 33/533 (2013.01); G01N 33/57496 (2013.01); G01N 33/583 (2013.01); G01N 2500/10 (2013.01); G01N 2510/00 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to a method for labeling or targeting cells whose plasma membrane has lost integrity, such as dead cells, such as for discriminating between live cells and cells whose plasma membrane has lost integrity; to an embodiment of the method for determining one or more values of one or more parameters of cells of a biological sample; to use of the method in an assay for screening drugs for therapy such as cancer therapy; to use of the method to monitor and/or determine the effectiveness of a therapy; to an assay kit; to a complex; to the complex for use as a medicament; to the complex for use in treatment of cancer(s) and/or plaque(s) and/or regeneration and/or supporting the immune system; and, to a dead cell.


Find Patent Forward Citations

Maring, Markwin. (2025). Protein target complex (U.S. Patent No. 12504428). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12504428

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