The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2025

Filed:

Oct. 26, 2022
Applicant:

Isoplexis Corporation;

Inventors:

Peter Tsiomplikas, Bridgeport, CT (US);

Jerry Sedgewick, St. Paul, MN (US);

Jeffrey Whynall, Killingworth, CT (US);

Sean Mackay, New Haven, CT (US);

Colin Ng, Branford, CT (US);

Patrick Paczkowski, East Haven, CT (US);

Sean Mccusker, Pleasanton, CA (US);

Igor Nikonorov, Whitestone, NY (US);

Alaina Kaiser, West Haven, CT (US);

Assignee:

IsoPlexis Corporation, Branford, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); B01L 3/00 (2006.01); G01N 33/487 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6458 (2013.01); B01L 3/502761 (2013.01); G01N 33/487 (2013.01); G01N 33/543 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/04 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0851 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/0893 (2013.01);
Abstract

Embodiments of the current disclosure are directed to systems, methods and apparatus for evaluating single cell secretion profiles. In some embodiments, the apparatus may be configured to analyze substances expressed by a biological cell and may include a first compressible substrate, and a second substrate configured for removable sealing attachment with the first substrate. In some embodiments, upon attachment of the second substrate with the first substrate, an assembly is formed such that the open side of the plurality of chambers are covered by the second substrate, and a portion of each of the plurality of capture areas are exposed in each of the chambers.


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