The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2025

Filed:

Nov. 27, 2020
Applicants:

Centre National DE LA Recherche Scientifique, Paris, FR;

Ecole Normale Superieure DE Paris, Paris, FR;

Sorbonne Universite, Paris, FR;

Inventors:

Raja Chouket, Paris, FR;

Vincent Croquette, Antony, FR;

Agathe Espagne, Montrouge, FR;

Ludovic Jullien, Arcueil, FR;

Annie Lemarchand, Villemoisson sur Orge, FR;

Thomas Le Saux, Puteaux, FR;

Agnès Pellissier-Tanon, Saint-Cloud, FR;

Ruikang Zhang, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); G01N 21/6408 (2013.01); G01N 21/6458 (2013.01); G01N 2021/6419 (2013.01); G01N 2021/6441 (2013.01);
Abstract

A method for detecting a reversibly photoswitchable chemical species in a sample, includes the steps of: a) illuminating the sample with light suitable to be absorbed by the chemical species triggering a reaction affecting an optical property of the chemical species, the first light being periodically-modulated at a fundamental modulation frequency; b) measuring the evolution of the optical property; c) extracting at least one of an in-phase component at a frequency which is an even multiple of the fundamental modulation frequency; and a quadrature component at a frequency which is an odd multiple of the fundamental modulation frequency of a signal representing the evolution; and d) using the extracted component or components for detecting the chemical species. An apparatus for carrying out the method is also provided.


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