The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
Feb. 12, 2021
Applicant:
Glaxosmithkline Intellectual Property (No.3) Limited, Stevenage, GB;
Inventors:
Nathalie Chauret, Laval, CA;
Jeremy Green, Waltham, MA (US);
David R. Kronenthal, Yardley, PA (US);
Karine Villeneuve, Laval, CA;
Assignee:
GlaxoSmithKline Intellectual Property (No.3) Limited, Stevenage, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 265/30 (2006.01); C07F 9/40 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 265/30 (2013.01); C07F 9/4006 (2013.01);
Abstract
Described herein are two processes for the preparation of methyl (5)-2-((2-(2,6-difLuoro-4-(methylcarbamol)phenyl)-7-methylimidaz[1,2-a]pyridine-3-yl)methyl)morpholine-4-carboxylate, a P2X3 antagonist, in a stepwise manner and chemical intermediates used in the synthetic processes.