The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
Jun. 03, 2020
Applicant:
Exelixis, Inc., Alameda, CA (US);
Inventors:
Lynne Canne Bannen, Novato, CA (US);
Minna Bui, Oakland, CA (US);
Faming Jiang, Castro Valley, CA (US);
Kin Tso, San Francisco, CA (US);
Yong Wang, South San Francisco, CA (US);
Wei Xu, Danville, CA (US);
Assignee:
Exelixis, Inc., Alameda, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/233 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 407/04 (2006.01); C07D 407/14 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 215/233 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 407/04 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01);
Abstract
Disclosed herein are compounds of Formula (I) which inhibit, regulate and/or modulate tyrosine kinase receptors, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities, compositions containing the compounds, methods of using the compounds to treat kinase-dependent diseases and conditions, and methods for making the compounds.