The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
Apr. 08, 2020
University of Georgia Research Foundation, Inc., Athens, GA (US);
Lohitash Karumbaiah, Bogart, GA (US);
Meghan T. Logun, Marietta, GA (US);
Leidong Mao, Watkinsville, GA (US);
Wujun Zhao, Waunakee, WI (US);
Yang Liu, Bogart, GA (US);
Chaitanya Tondepu, San Francisco, CA (US);
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC., Athens, GA (US);
Abstract
Described herein is a microfluidic assay device that mimics in vitro the in vivo biological environment, supporting endothelization, allowing for perfusive flow similar to in vivo blood flow conditions, and providing for realistic interactions between T-cells and solid tumor cells, such as glioblastoma multiforme tumor cells. Also described herein are methods of using this microfluidic assay device for the study of interactions of immune cells with tumor cells, such as glioblastoma multiforme tumor cells, and the development of improved immunotherapeutic approaches against cancers, such as glioblastoma multiforme.