The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
Oct. 29, 2020
Daegu-gyeongbuk Medical Innovation Foundation, Daegu, KR;
Ji-Hoon Yu, Daegu, KR;
Chun Young Im, Daegu, KR;
So Young Kim, Daegu, KR;
Ye Ri Han, Daegu, KR;
Doohyun Lee, Daegu, KR;
Hui-Jeon Jeon, Daegu, KR;
Sang-Hyun Min, Daegu, KR;
Bae Jun Oh, Daegu, KR;
Sang-Wook Park, Daegu, KR;
Dong-Kyu Choi, Daegu, KR;
Young-Kyu Kim, Daegu, KR;
Sung Hwan Kim, Daegu, KR;
Yuri Lee, Daegu, KR;
Seungyeon Lee, Daegu, KR;
Nam Hui Kim, Daegu, KR;
Sang Bum Kim, Daegu, KR;
Ju-Sik Min, Daegu, KR;
DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION, Daegu, KR;
Abstract
The present invention relates to a compound comprising an EZH2 inhibitor and an E3 ligase binder, and a pharmaceutical composition for preventing or treating EZH2-associated disease and a pharmaceutical composition for selective protein degradation containing the same as an active ingredient. Since the compound of the present invention can selectively degrade EZH2, it can be effectively used for the treatment of EZH2-related diseases and cancers, particularly, cancers in which EZH2 is overexpressed, and can be usefully used for the selective degradation of EZH2.