The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 23, 2025

Filed:

Jul. 22, 2019
Applicant:

Minovia Therapeutics Ltd., Tirat Hacarmel, IL;

Inventors:

Natalie Yivgi Ohana, Haifa, IL;

Uriel Halavee, Tel Aviv, IL;

Shmuel Bukshpan, Ramat Hasharon, IL;

Noa Sher, Haifa, IL;

Moriya Blumkin, Tel Aviv, IL;

Assignee:

Minovia Therapeutics Ltd., Tirat Hacarmel, IL;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/545 (2015.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
A61K 35/545 (2013.01); A61K 35/28 (2013.01);
Abstract

The present invention provides human stem cells enriched with functional mitochondria, wherein the healthy functional exogenous mitochondria constitute at least 3% and less than 33% of the total mitochondria in the mitochondrially-enriched human stem cells. Further disclosed are methods for the production of such cells, and uses thereof for the treatment of primary mitochondrial diseases.


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