The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
May. 26, 2021
Jiangsu Yahong Meditech Co., Ltd., Jiangsu, CN;
Asieris Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, CN;
Jie Chen, Jiangsu, CN;
Shuai Shen, Jiangsu, CN;
Youbin Wu, Jiangsu, CN;
Jianghua Liu, Jiangsu, CN;
Yushen Guo, Shanghai, CN;
Jiangsu Yahong Meditech Co., Ltd., Jiangsu, CN;
Asieris Pharmaceuticals (Shanghai) Co., Ltd., Shanghai, CN;
Abstract
A pharmaceutical composition containing a nitroxoline prodrug, and a preparation method and an application therefor. The pharmaceutical composition comprises the following ingredients in parts by weight: 100 parts of active pharmaceutical ingredient, 22.5-320 parts of filler, 0-40 parts of disintegrant, 0-95 parts of binding agent, and 2-30 parts of lubricant; relative to each 100 parts by weight of active pharmaceutical ingredient, the total content of the filler, the disintegrant, and the binding agent is 54-345 parts by weight; the active pharmaceutical ingredient is (S)-(5-nitroxoline-8-yloxy)methyl 1-isopropylpyrrolidine-2-carboxylate. The pharmaceutical composition has good stability, dissolution properties, and pharmacokinetic characteristics.