The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
Jul. 21, 2020
Applicant:
Vanda Pharmaceuticals Inc., Washington, DC (US);
Inventors:
Michel Burcklen, Allschwil, CH;
Tarek El Akkad, Chester, NJ (US);
Brian Hennessy, Allschwil, CH;
Andrea Vaclavkova, Allschwil, CH;
Alexander Keenan, Raritan, NJ (US);
Assignee:
Vanda Pharmaceuticals Inc., Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/54 (2006.01); A61K 31/426 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); A61P 25/28 (2018.01);
Abstract
The disclosure relates to methods of treating multiple sclerosis using Ponesimod. In certain aspects, these include methods of avoiding worsening of fatigue-related symptoms in a human patient who has had no prior disease modifying treatment (DMT) for multiple sclerosis, who has a baseline expanded disability status scale (EDSS) score of ≤3.5, or who does not have Gd+/T1 lesions at baseline.