The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 23, 2025
Filed:
May. 16, 2018
Saint Louis University, St. Louis, MO (US);
United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);
The Research Foundation of the City University of New York, New York, NY (US);
Feng Cao, Olivette, MO (US);
John E. Tavis, Kirkwood, MO (US);
Maureen J. Donlin, Kirkwood, MO (US);
Marvin J. Meyers, Wentzville, MO (US);
Ryan P. Murelli, Belleville, NJ (US);
Cari Orth, St. Louis, MO (US);
Bahaa Elgendy, St. Louis, MO (US);
Saint Louis University, St. Louis, MO (US);
United States Government as Represented by the Department of Veterans Affairs, Washington, DC (US);
Research Foundation of the City University of New York, New York, NY (US);
Abstract
In one aspect, the present disclosure provides methods of treating a bacterial infection using an inhibitor of the nucleotidyltransferase superfamily enzyme. In some embodiments, the compounds have one of the following formulas (I), (II), (III), or (IV) wherein R, R, and Rare as defined herein or a pharmaceutically acceptable salt thereof. The compounds may be used to treat a bacterial infection including an infection of, andspecies.