The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2025

Filed:

May. 18, 2020
Applicant:

Tonghua Dongbao Pharmaceutical Co., Ltd., Jilin, CN;

Inventors:

Depeng Wang, Jilin, CN;

Shanshan Wei, Jilin, CN;

Xindan Fan, Jilin, CN;

Zhongyu Zhang, Jilin, CN;

Nan Zhang, Jilin, CN;

Chunsheng Leng, Jilin, CN;

Xiaohui Chang, Jilin, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); A61K 39/00 (2006.01); A61K 47/18 (2017.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); A61K 2039/545 (2013.01);
Abstract

Provided are a stable secukinumab injection and a preparation method therefor. The stable secukinumab injection is composed of the following ingredients: 50 mg/ml-300 mg/ml of secukinumab, 5 mmol/L-50 mmol/L of histidine and a histidine hydrochloride, 5 mmol/L-50 mmol/L of methionine, 150 mmol/L-400 mmol/L of a low-sugar alcohol, and 0.01%-0.02 of polysorbate 80, wherein the balance is water for injection, and the pH is 5.0-7.0. Stability tests prove that the quality of the stable secukinumab injection is stable, wherein the stability thereof is superior to that of commercial varieties on the market, and same has various indicators that meet the relevant regulations of the Chinese Pharmacopoeia, and has good application prospects.


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