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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12497412 B1

PDFFull Text
Date of Patent:
Dec. 16, 2025

Filed:

Nov. 18, 2020

Compound as highly selective ros1 inhibitor and use thereof

Applicant:

Guangzhou Joyo Pharmatech Co., Ltd, Guangdong, CN;

Inventors:

Jianfei Wang, Shanghai, CN;

Guangwen Yang, Shanghai, CN;

Jikui Sun, Shanghai, CN;

Zhihua Ao, Shanghai, CN;

Peng Li, Shanghai, CN;

Yang Zhang, Shanghai, CN;

Qiu Li, Shanghai, CN;

Jian Li, Shanghai, CN;

Shuhui Chen, Shanghai, CN;

Assignee:

GUANGZHOU JOYO PHARMATECH CO., LTD., Guangdong, CN;

Attorney:

Harness, Dickey & Pierce, P.L.C.

Primary Examiner:

Jeffrey S Lundgren

Assistant Examiner:

Heather undefined Dahlin

Int. Cl.
CPC ...
C07D 498/22 (2006.01); A61P 11/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); A61P 11/00 (2018.01); A61P 35/00 (2018.01);
Abstract

Disclosed are a class of compounds having a highly selective inhibition of ROS1, and the use thereof in the preparation of drugs for treating diseases related to abnormal ROS1 kinase expression. Specifically disclosed are compounds represented by formula (IV) and a pharmaceutically acceptable salt thereof.

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Wang, Jianfei. (2025). Compound as highly selective ros1 inhibitor and use thereof (U.S. Patent No. 12497412). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12497412

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