The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2025
Filed:
May. 29, 2020
Shanghai Hansoh Biomedical Co., Ltd., Shanghai, CN;
Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Lianyungang, CN;
Shiqiang Liu, Shanghai, CN;
Yongsheng Wang, Shanghai, CN;
Yida Yuan, Shanghai, CN;
Cheng Cen, Shanghai, CN;
Rudi Bao, Shanghai, CN;
SHANGHAI HANSOH BIOMEDICAL CO., LTD., Shanghai, CN;
JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD., Lianyungang, CN;
Abstract
Disclosed are a nitrogen-containing heterocyclic derivative regulator, a preparation method therefor and an application thereof. In particular, disclosed are a compound as represented by general formula (I), a preparation method for the compound and a pharmaceutical composition containing the compound, and the use thereof as a KRAS G12C mutation inhibitor in treatment of diseases or symptoms such as leukemia, neuroblastoma, melanoma, breast cancer, lung cancer and colon cancer, wherein the definitions of substituents in general formula (I) are the same as those in the description.