The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2025

Filed:

May. 29, 2020
Applicants:

Shanghai Hansoh Biomedical Co., Ltd., Shanghai, CN;

Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Lianyungang, CN;

Inventors:

Shiqiang Liu, Shanghai, CN;

Yongsheng Wang, Shanghai, CN;

Yida Yuan, Shanghai, CN;

Cheng Cen, Shanghai, CN;

Rudi Bao, Shanghai, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 35/00 (2018.01); C07D 519/00 (2013.01);
Abstract

Disclosed are a nitrogen-containing heterocyclic derivative regulator, a preparation method therefor and an application thereof. In particular, disclosed are a compound as represented by general formula (I), a preparation method for the compound and a pharmaceutical composition containing the compound, and the use thereof as a KRAS G12C mutation inhibitor in treatment of diseases or symptoms such as leukemia, neuroblastoma, melanoma, breast cancer, lung cancer and colon cancer, wherein the definitions of substituents in general formula (I) are the same as those in the description.


Find Patent Forward Citations

Liu, Shiqiang. (2025). Nitrogen-containing heterocyclic derivatives, method therefor and application therefor as inhibitors of kras g12c for the treatment of cancers (U.S. Patent No. 12497396). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12497396

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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