The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2025
Filed:
Sep. 25, 2020
Hinova Pharmaceuticals Inc., Sichuan, CN;
Lei Fan, Sichuan, CN;
Fei Wang, Sichuan, CN;
Xiaoquan Wu, Sichuan, CN;
Kexin Xu, Sichuan, CN;
Tongchuan Luo, Sichuan, CN;
Shaohua Zhang, Sichuan, CN;
Yongxu Huo, Sichuan, CN;
Xinghai Li, Sichuan, CN;
Yuanwei Chen, Sichuan, CN;
HINOVA PHARMACEUTICALS INC., Sichuan, CN;
Abstract
An EP300/CBP inhibitor, specifically provided is a compound as shown in formula I, or a deuterated product thereof, or a salt thereof, or a conformational isomer thereof, or a crystal form thereof, or a solvate thereof. The compound is highly selective for EP300/CBP, and can effectively inhibit the activity of EP300/CBP; in addition, the compound has an excellent inhibitory effect on various tumor cells including prostate cancer cells, leukemia cells, breast cancer cells and multiple myeloma cells. The compound has broad application prospects in the preparation of an EP300/CBP inhibitor, and drugs for preventing and/or treating tumors, myeloid hematopoietic stem/progenitor cells malignant disease, and regulating regulatory T cells.