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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12497385 B1

PDFFull Text
Date of Patent:
Dec. 16, 2025

Filed:

Dec. 17, 2021

Photoprotective compositions containing-derived compounds and/or chemical analogs thereof

Applicant:

Versicolor Technologies, Llc, Santa Monica, CA (US);

Inventors:

Michael Einziger, Malibu, CA (US);

Ann Marie Simpson, Malibu, CA (US);

Assignee:

VERSICOLOR TECHNOLOGIES, LLC, Santa Monica, CA (US);

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Primary Examiner:

Joseph K Mckane

Assistant Examiner:

Sagar undefined Patel

Int. Cl.
CPC ...
A61K 31/405 (2006.01); A61K 8/49 (2006.01); A61K 31/404 (2006.01); A61K 31/4045 (2006.01); A61K 31/407 (2006.01); A61K 31/55 (2006.01); A61P 17/00 (2006.01); A61Q 17/04 (2006.01); A61Q 19/02 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); A61K 8/494 (2013.01); A61K 8/4973 (2013.01); A61K 31/404 (2013.01); A61K 31/407 (2013.01); A61K 31/55 (2013.01); A61Q 19/02 (2013.01); C07D 405/06 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to compounds, compositions, and methods for modulating skin pigmentation and treating or preventing UV-induced skin damage, erythema, aging of the skin, sunburn, and hyperpigmentation in a subject. The compounds, compositions, and methods of the present invention generally involve-derived compounds, including malassezin and indirubin, and/or chemical analogs thereof. Other applications of the compounds and compositions disclosed herein include, but are not limited to, improving hyperpigmentation caused by a hyperpigmentation disorder, inducing melanocyte apoptosis, and modulating arylhydrocarbon receptor (AhR) activity, melanogenesis, melanin production, melanosome biogenesis, melanosome transfer, melanocyte activity, and melanin concentration.

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