The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2025

Filed:

Apr. 30, 2021
Applicant:

Exelixis, Inc., Alameda, CA (US);

Inventors:

Frenel Demorin, Long Beach, CA (US);

Khalid Shah, Half Moon Bay, CA (US);

Sagar Shakya, San Diego, CA (US);

Yong Wang, Foster City, CA (US);

Wei Xu, Danville, CA (US);

Assignee:

Exelixis, Inc., Alameda, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/48 (2006.01);
U.S. Cl.
CPC ...
C07D 215/48 (2013.01);
Abstract

The present invention relates to processes for the synthetic preparation of c-Met inhibitors of Formula I, or pharmaceutically acceptable salts thereof. The present invention further relates to processes for the synthetic preparation of the c-Met inhibitor, Compound 1, or a pharmaceutically acceptable salt thereof. The present invention also relates to processes for the synthetic preparation of Compound 1·hemifumarate. The invention further relates to large scale processes for the synthetic preparation of the c-Met inhibitor, Compound 1 and Compound 1·hemifumarate.


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