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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12497366 B1

PDFFull Text
Date of Patent:
Dec. 16, 2025

Filed:

Apr. 14, 2025

Nitrogen-containing heterocyclic derivative inhibitor, preparation method therefor and use thereof

Applicants:

Shanghai Hansoh Biomedical Co., Ltd., Shanghai, CN;

Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Jiangsu, CN;

Inventors:

Jiaqiang Dong, Shanghai, CN;

Xinxian Deng, Shanghai, CN;

Wensheng Yu, Shanghai, CN;

Fangfang Jin, Shanghai, CN;

Zhen Gong, Shanghai, CN;

Assignees:

SHANGHAI HANSOH BIOMEDICAL CO., LTD., Shanghai, CN;

JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD., Jiangsu, CN;

Attorneys:

Pilloff Passino & Cosenza LLP

Rachel Pilloff

Sean Passino

Primary Examiner:

Joseph K Mckane

Assistant Examiner:

David M Shim

Int. Cl.
CPC ...
C07D 213/75 (2006.01); A61K 31/444 (2006.01); A61K 31/497 (2006.01); A61K 31/4985 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/52 (2006.01); A61K 31/53 (2006.01); A61K 31/541 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/553 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 473/32 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 491/052 (2006.01); C07D 498/14 (2006.01); C07D 513/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 213/75 (2013.01); A61K 31/444 (2013.01); A61K 31/497 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/52 (2013.01); A61K 31/53 (2013.01); A61K 31/541 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/553 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 473/32 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01); C07D 498/14 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01);
Abstract

A nitrogen-containing heterocyclic derivative inhibitor, a preparation method therefor and the use thereof. Specifically disclosed are a compound as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof as an inhibitor in treating diseases such as cardiovascular and cerebrovascular diseases, wherein the definition of each substituent in the general formula (I) are the same as those defined in the description.

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