The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2025
Filed:
Dec. 18, 2020
Universita Degli Studi Di Firenze, Florence, IT;
Gabriella Caminati, Sesto Fiorentino, IT;
Piero Procacci, Sesto Fiorentino, IT;
Stefano Menichetti, Sesto Fiorentino, IT;
Maria Raffaella Martina, Sesto Fiorentino, IT;
Laura Marsili, Sesto Fiorentino, IT;
UNIVERSITA DEGLI STUDI DI FIRENZE, Florence, IT;
Abstract
The present invention relates to novel compounds useful as sensors for the rapid and specific determination of the FKBP12 protein, a peptidyl-prolyl cis-trans isomerase (PPlase), the levels of which in the biological fluids of a subject change if the subject is affected by pathological conditions, in particular neurodegenerative diseases, such as the Parkinson's disease and the Alzheimer's syndrome, tumour pathologies, autoimmune diseases, or if that subject is in a phase of acute rejection after organ transplantation.