The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2025

Filed:

Aug. 16, 2021
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Stephane L. Bogen, Somerset, NJ (US);

Dane James Clausen, Rahway, NJ (US);

Michael T. Rudd, Collegeville, PA (US);

Dong Xiao, Warren, NJ (US);

Dexi Yang, Livingston, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/52 (2006.01); A61K 31/403 (2006.01); A61K 31/407 (2006.01); A61K 31/506 (2006.01); A61P 25/00 (2006.01); C07D 401/14 (2006.01); C07D 491/02 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 209/52 (2013.01); A61K 31/403 (2013.01); A61K 31/407 (2013.01); A61K 31/506 (2013.01); A61P 25/00 (2018.01); C07D 401/14 (2013.01); C07D 491/02 (2013.01); C07D 491/048 (2013.01);
Abstract

The present invention is directed to cyclopentapyrrole, furopyrrole and azabicycloheptane compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.


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