The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2025

Filed:

Jan. 21, 2021
Applicant:

Trustees of Dartmouth College, Hanover, NH (US);

Inventors:

Alberto J. Ruiz, Hanover, NH (US);

Ethan P. M. Larochelle, Thetford Center, VT (US);

Brian Pogue, Hanover, NH (US);

Assignee:

Trustees of Dartmouth College, Hanover, NH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 5/06 (2006.01); A61B 5/00 (2006.01); A61N 5/067 (2006.01);
U.S. Cl.
CPC ...
A61N 5/062 (2013.01); A61B 5/0059 (2013.01); A61N 2005/063 (2013.01); A61N 5/067 (2021.08);
Abstract

While clinical treatment of actinic keratosis by photodynamic therapy (PDT) is widely practiced, there is well-known variability in response, primarily caused by heterogeneous accumulation and PDT-induced photobleaching of the photosensitizer protoporphyrin IX (PpIX) between patients and between lesions. One of the key factors in regularizing this treatment would be to have an easily accessible indicator of PpIX present in the lesions at the time of light delivery. Described herein, a smartphone-based fluorescence imager was developed to allow simple quantitative photography of the lesions and their PpIX levels.


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