The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 2025
Filed:
Oct. 27, 2019
Applicant:
Board of Regents of the University of Nebraska, Lincoln, NE (US);
Inventors:
Dong Wang, Omaha, NE (US);
Steven R. Goldring, Auburndale, MA (US);
Gang Zhao, Omaha, NE (US);
Rongguo Ren, Omaha, NE (US);
Zhenshan Jia, Omaha, NE (US);
Xin Wei, Omaha, NE (US);
Assignee:
BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA, Lincoln, NE (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/58 (2017.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 47/58 (2017.08); A61K 47/6903 (2017.08);
Abstract
This application discloses prodrug-based thermosensitive gel ('ProGel') comprised of conjugates of dmg molecules with water-soluble polymeric carriers, which are capable of controlled release of the dmg molecules into the tissue of a subject. Use of the ProGel-Drug conjugates for treatment of various diseases or disorders and methods of preparing them are also disclosed.