The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 16, 2025

Filed:

Nov. 12, 2020
Applicant:

Bausch + Lomb Ireland Limited, Dublin, IE;

Inventors:

Mark S. Blumenkranz, Portola Valley, CA (US);

Yehuda Ivri, Newport Coast, CA (US);

Reynaldo Quintana, Menlo Park, CA (US);

Daniel V. Palanker, Sunnyvale, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F 9/00 (2006.01); G16H 20/13 (2018.01); G16H 40/67 (2018.01);
U.S. Cl.
CPC ...
A61F 9/0008 (2013.01); G16H 20/13 (2018.01); G16H 40/67 (2018.01);
Abstract

The efficacy of a dosing regimen can be altered, and preferably improved, by fractionating the doses. Here fractionating the doses can be regarded as taking a single conventional dose and splitting that dose into two or more dose-fractions delivered at relatively short time intervals, where the dose-fractions add up to the same total dose as the conventional dose. In cases where dose fractionation increases the therapeutic effect, this can result in a greater therapeutic effect from a smaller total dose when the doses are fractionated. This effect has been demonstrated in an ophthalmic application, but is expected to be more generally applicable.


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