The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2025

Filed:

Jul. 08, 2021
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD (US);

Inventors:

Magdoom Mohamed Kulam Najmudeen, Bethesda, MD (US);

Peter J. Basser, Bethesda, MD (US);

Michal E. Komlosh, Bethesda, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 33/563 (2006.01); G01R 33/022 (2006.01); G01R 33/24 (2006.01);
U.S. Cl.
CPC ...
G01R 33/56341 (2013.01); G01R 33/022 (2013.01); G01R 33/246 (2013.01);
Abstract

Diffusion sensitizing gradient pulse pairs are prescribed in a manner to mitigate effects of concomitant gradient artifacts. Measured MR signals generated by applying a plurality of diffusion sensitizing gradient matrices are obtained and processed to determine a second order mean diffusion tensor and a fourth order covariance tensor. Quantities derived from these tensors are measured and mapped within an imaging volume which describe features of diffusion anisotropy and heterogeneity within each imaging voxel.


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