The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2025

Filed:

Feb. 01, 2023
Applicants:

Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;

Istituto Giannina Gaslini, Genoa, IT;

Fondazione Per LA Ricerca Sulla Fibrosi Cistica—onlus, Verona, IT;

Inventors:

Tiziano Bandiera, Genoa, IT;

Fabio Bertozzi, Genoa, IT;

Paolo Di Fruscia, Genoa, IT;

Federico Sorana, Verona, IT;

Emanuela Caci, Verona, IT;

Loretta Ferrera, Verona, IT;

Nicoletta Pedemonte, Genoa, IT;

Luis Juan Vicente Galietta, Genoa, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/415 (2006.01); C07D 231/16 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61K 31/415 (2013.01); C07D 231/16 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular to modulate CFTR protein or ABC protein activities.


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