The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2025
Filed:
Mar. 26, 2021
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Jacqueline D. Hicks, Watchung, NJ (US);
Amjad Ali, Freehold, NJ (US);
John S. Debenham, South Plainfield, NJ (US);
Anthony Donofrio, Cambridge, MA (US);
Wenlang Fu, Madison, NJ (US);
Ying-Duo Gao, Middletown, NJ (US);
Alan Hruza, Hackettstown, NJ (US);
Yeon-Hee Lim, South San Francisco, CA (US);
Matthew J. Lombardo, Flemington, NJ (US);
Peter Nizner, Fanwood, NJ (US);
Sung-Sau So, Verona, NJ (US);
Zheng Tan, Westfield, NJ (US);
Daniel A. Tatosian, Berkeley Heights, NJ (US);
Dong Xiao, Warren, NJ (US);
Dexi Yang, Livingston, NJ (US);
Yang Yu, Edison, NJ (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XI activation inhibitors.