The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2025
Filed:
Dec. 06, 2021
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Antonella Converso, Elkins, PA (US);
David N. Hunter, Hatfield, PA (US);
Abdellatif El Marrouni, Ambler, PA (US);
Anthony J. Roecker, Harleysville, PA (US);
Anthony W. Shaw, Harleysville, PA (US);
William D. Shipe, Chalfont, PA (US);
Cheng Wang, Fort Washington, PA (US);
Deping Wang, Sharon, MA (US);
Yunlong Zhang, Valhalla, NY (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The present disclosure is directed to tetrahydroquinazoline derivatives of Formula (I) and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV naive cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).