The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2025

Filed:

Jul. 19, 2024
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Institute of Organic Chemistry and Biochemistry As CR V.v.i., Prague, CZ;

Inventors:

Barbara Slusher, Baltimore, MD (US);

Mohameed Islam, Baltimore, MD (US);

Rana Rais, Baltimore, MD (US);

Luis Garza, Baltimore, MD (US);

Benjamin Bell, Baltimore, MD (US);

Pavel Majer, Kretin, CZ;

Lukas Tenora, Prague, CZ;

Ivan Snajdr, Prague, CZ;

Marcela Krecmerova, Prague, CZ;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/225 (2006.01); C07C 69/593 (2006.01); C07C 229/36 (2006.01); C07C 237/12 (2006.01); C07C 271/22 (2006.01);
U.S. Cl.
CPC ...
C07C 69/593 (2013.01); A61K 31/225 (2013.01); C07C 229/36 (2013.01); C07C 237/12 (2013.01); C07C 271/22 (2013.01);
Abstract

Prodrugs of itaconic acid and 1- and 4-methyl itaconic acid and their use for treating a disease, disorder, or condition associated with inflammation are disclosed.


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