The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 09, 2025

Filed:

Oct. 30, 2020
Applicant:

Tohoku University, Sendai, JP;

Inventors:

Tokunori Yamamoto, Nagoya, JP;

Shinobu Shimizu, Nagoya, JP;

Akira Furuta, Tokyo, JP;

Mari Dezawa, Sendai, JP;

Yasumasa Kuroda, Sendai, JP;

Assignee:

TOHOKU UNIVERSITY, Sendai, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 35/545 (2015.01); A61P 13/10 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 35/545 (2013.01); A61P 13/10 (2018.01);
Abstract

The purpose of the present invention is to provide a novel medical application using pluripotent stem cells in regenerative medicine. The present invention provides a cell formulation and pharmaceutical composition that are for amelioration and therapy for frequent urination and bladder pain caused by the inflammation of the bladder and that contain SSEA-3 positive pluripotent stem cells isolated from cultured mesenchymal cells or a mesenchymal tissue of a living organism. The cell formulation according to the present invention is considered to be based on a mechanism in which, for example, Muse cells are administered against interstitial cystitis having the abovementioned disorders to be successfully engrafted into affected bladder tissue, whereby the disorders are ameliorated and treated.


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