The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2025
Filed:
Sep. 21, 2021
Wisconsin Alumni Research Foundation, Madison, WI (US);
Mario Otto, Fitchburg, WI (US);
Dana C. Baiu, Madison, WI (US);
Bryan P. Bednarz, Madison, WI (US);
Jamey Paul Weichert, Sun Prairie, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by malignant pediatric tumor cells. The alkylphophocholine analogs are compounds having the formula: or salts thereof, wherein n is an integer from 12 to 24; and Ris —N(CH). The compounds can be used to treat pediatric solid tumors or to detect pediatric solid tumors. In therapeutic treatment, Rincludes a radioactive iodine isotope that locally delivers therapeutic dosages of radiation to the malignant pediatric tumor cells that preferentially take up the compound. In detection/imaging applications, Rincludes a detection moiety, such as a fluorophore or a radioactive iodine isotope.