The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2025
Filed:
Nov. 12, 2021
Nantcell, Culver City, CA (US);
Nant Holdings Ip, Llc, Culver City, CA (US);
Shahrooz Rabizadeh, Agoura Hills, CA (US);
Kayvan Niazi, Culver City, CA (US);
Patrick Soon-Shiong, Culver City, CA (US);
Hing Wong, Weston, FL (US);
Wenxin Xu, Pembroke Pines, FL (US);
ImmunityBio, Inc., San Diego, CA (US);
NantCell, Inc., Culver City, CA (US);
Abstract
Contemplated treatments and methods produce substantially increased quantities of memory T-cells and a persistent immune response by subcutaneous and/or subdermal co-administration of (1) a vector comprising a recombinant nucleic acid that encodes a cancer associated epitope, a cancer specific epitope, and/or a neoepitope, (2) an immune stimulating cytokine, and (3) a checkpoint inhibitor. Most typically, the co-administration is performed at substantially the same location, preferably within 1-21 days from each other, and the vector is an adenoviral expression vector, for example, included in a viral particle such as an AdV5 virus with a deletion of the E2b gene.