The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2025
Filed:
Jul. 15, 2020
Universidade DE São Paulo, São Paulo, BR;
Universidade DE Coimbra, Coimbra, PT;
Amanda Cristina Zangirolami, São Carlos, BR;
Kate Cristina Blanco, São Carlos, BR;
Vanderlei Salvador Bagnato, São Carlos, BR;
Natalia Mayumi Inada, São Carlos, BR;
Carolina Dos Santos Vinagreiro, Coimbra, PT;
Lucas Danilo Dias, Coimbra, PT;
Luís Guilherme Da Silva Arnaut Moreira, Coimbra, PT;
Maria Miguens Pereira, Coimbra, PT;
UNIVERSIDADE DE SÃO PAULO, São Paulo, BR;
UNIVERSIDADE DE COIMBRA, Coimbra, PT;
Abstract
The present invention describes methods for obtaining functionalized polymeric surfaces (MPn-PSm) from polymers or copolymers with appropriate functionalizations (X), which can be a halogen of a leaving group, such as polyvinyl chloride (MP1) and (chloromethyl) polystyrene-Merrifield (MP2), and curcumin photosensitizers (PS1), meso-tetra(aryl) porphyrins, chlorins or bacteriochlorins halogenated and functionalized with nucleophilic groups (PS2), in particular including P2 of the type meso-imidazoyl-porphyrins, chlorins or bacteriochlorins (PS3). The structures of all the photosensitizers in the present application incorporate a functional group (Y), which is a OH, SH or NH 2 nucleophile. The application also describes the covalent bonding process of the photosensitizers PS1-PS3 to the functional polymeric materials MP1-MP2 by means of a nucleophilic substitution reaction to prepare the MPn-Psm products. The formed products prevent microbial proliferation, which can cause the serious infections that are one of the main causes of death in patients using these devices.