The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2025

Filed:

Mar. 11, 2021
Applicant:

City of Hope, Duarte, CA (US);

Inventors:

Michael Kahn, Monrovia, CA (US);

David Horne, Altadena, CA (US);

Assignee:

CITY OF HOPE, Duarte, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Disclosed and provided herein are, inter alia, compounds of formula (Ia), (Ib), or (Ic): or pharmaceutically acceptable salts or stereoisomers thereof, and use thereof in methods for modulating CREB binding protein (CBP)/catenin signaling pathway activity and treating CBP/β-catenin mediated disorders.


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