The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2025
Filed:
Feb. 27, 2023
Southern Research Institute, Birmingham, AL (US);
Uab Research Foundation, Birmingham, AL (US);
Kevin Jay Rodzinak, Moody, AL (US);
Terry Smalley, Greensboro, NC (US);
Robert Hunter, Garner, NC (US);
John P. Tillotson, Birmingham, AL (US);
Corinne E. Augelli-Szafran, Homewood, AL (US);
Bini Mathew, Hoover, AL (US);
David Bedwell, Hoover, AL (US);
Steven Rowe, Birmingham, AL (US);
SOUTHERN RESEARCH INSTITUTE, Birmingham, AL (US);
UAB RESEARCH FOUNDATION, Birmingham, AL (US);
Abstract
The present disclosure is concerned with substituted uracil compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders associated with the presence of a premature termination codon such as, for example, cystic fibrosis, Duchenne muscular dystrophy, aniridia, Becker muscular dystrophy, spinal muscular atrophy, Hurler syndrome, hemophilia, epidermolysis bullosa (e.g., dystrophic (DEB) form, junctional (JEB) form), Usher syndrome, and cancer, using the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.