The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2025
Filed:
Jul. 14, 2022
Applicant:
Cornell University, Ithaca, NY (US);
Inventors:
Kai Ma, Belle Mead, NJ (US);
Ulrich B. Wiesner, Ithaca, NY (US);
Assignee:
Cornell University, Ithaca, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 9/51 (2006.01); A61K 47/02 (2006.01); A61K 47/69 (2017.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 49/0093 (2013.01); A61K 9/5146 (2013.01); A61K 47/02 (2013.01); A61K 47/6923 (2017.08); A61K 49/0032 (2013.01); A61K 49/0043 (2013.01); A61K 49/0054 (2013.01); B82Y 5/00 (2013.01);
Abstract
Described is a versatile surface modification approach to, for example, modularly and orthogonally functionalize nanoparticles (NPs) such as, for example, PEGylated nanoparticles, ith various types of different functional ligands (functional groups) on the NP surface. It enables the synthesis of, for example, penta-functional PEGylated nanoparticles integrating a variety of properties into a single NP, e.g., fluorescence detection, specific cell targeting, radioisotope chelating/labeling, ratiometric pH sensing, and drug delivery, while the overall NP size remains, for example, below 10 nm.