The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2025

Filed:

Feb. 07, 2025
Applicant:

Beijing Youcare Kechuang Pharmaceutical Technology Co., Ltd., Beijing, CN;

Inventors:

Gengshen Song, Beijing, CN;

Honglei Zhang, Beijing, CN;

Yuting Zhou, Beijing, CN;

Lijie Jin, Beijing, CN;

Jinyu Zhang, Beijing, CN;

Kai Dong, Beijing, CN;

Huanyu Wang, Beijing, CN;

Xiaowen Yu, Beijing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 47/54 (2017.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 47/544 (2017.08); A61K 47/545 (2017.08); A61K 48/0033 (2013.01); A61K 2039/53 (2013.01); A61K 2039/55555 (2013.01);
Abstract

The present disclosure relates to the technical field of molecular biology and provides a lipid composition targeting antigen-presenting cells and a use thereof. The composition provided by the present disclosure demonstrates good organ and cell targeting specificity, significantly enhancing the protein expression level of antigens in the spleen. Additionally, the composition significantly increases the percentage of cells that express the antigen among antigen-presenting cells (e.g., B cells, pDC cells, cDC cells, and macrophages) in the spleen, indicating that the composition can be used in the immunotherapy of diseases.


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