The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2025

Filed:

Jan. 26, 2021
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Qian Zhang, Danville, CA (US);

Sanjeev Gangwar, Foster City, CA (US);

Ashvinikumar V. Gavai, Princeton Junction, NJ (US);

Qiang Cong, Palo Alto, CA (US);

Yam B. Poudel, Fremont, CA (US);

Liqi He, San Jose, CA (US);

Prasanna Sivaprakasam, Plainsboro, NJ (US);

Christine M. Tarby, Lawrenceville, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61K 39/395 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 39/3955 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.


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