The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2025

Filed:

Aug. 31, 2022
Applicant:

Aprecia Pharmaceuticals Llc, Mason, OH (US);

Inventors:

Jaedeok Yoo, Princeton, NJ (US);

Aleece M. Phillips, Yardley, PA (US);

Thomas J. Bradbury, Yardley, PA (US);

Thomas G. West, Lawrenceville, NJ (US);

Assignee:

APRECIA PHARMACEUTICALS LLC, Mason, OH (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0056 (2013.01); A61K 9/2077 (2013.01); A61K 9/2095 (2013.01);
Abstract

A rapidly-orodispersible dosage form comprising a porous, bound-powder matrix and one or more internal cavities is provided, as well as three-dimensional printing methods for making the same. Each internal cavity is configured to contain one or more payloads, particularly pharmaceutical medicaments, while isolating the payloads from the external environment outside of the dosage form. Each payload can be contained within its cavity in its native form without having to be combined with the bound-powder matrix or binding liquid. Dosage forms can disintegrate in water or saliva in less than two minutes, independently of the payload(s) or medicament(s) contained within. The dosage forms can be formed as unitary tablets, or as two-piece tablets comprising a container body and a lidding body that are secured together to isolate the one or more cavities and their payloads inside.


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