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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12482539 B1

PDFFull Text
Date of Patent:
Nov. 25, 2025

Filed:

May. 05, 2021

Robustness of hydrolases by combining high-pressure molecular dynamics simulation and free energy calculation

Applicant:

Jiangnan University, Wuxi, CN;

Inventors:

Xiaole Xia, Wuxi, CN;

Nan Zheng, Wuxi, CN;

Zehua Zhang, Wuxi, CN;

Assignee:

JIANGNAN UNIVERSITY, WUXI, CN;

Attorneys:

IPro, PLLC

QIAN GU

NA XU

Primary Examiner:

ROSSI, VY BUI

Int. Cl.
CPC ...
U.S. Cl.
CPC ...
G16C 10/00 ; G16B 40/00 ; G16B 15/00 ; G16B 20/50 ; G16B 5/20 ; G16B 15/20 ; C12N 9/20 ; C12N 9/80 ; C12Y 301/01003 ; C12Y 305/01075 ;

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Xia, Xiaole. (2025). Robustness of hydrolases by combining high-pressure molecular dynamics simulation and free energy calculation (U.S. Patent No. 12482539). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12482539

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