The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Feb. 01, 2019
Applicants:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Maastricht University Medical Center, Maastricht, NL;

Inventors:

Johann Karl, Peissenberg, DE;

Peter Kastner, Murnau am Staffelsee, DE;

Roberto Latini, Milan, IT;

Serge Masson, Monza, IT;

Ursula-Henrike Wienhues-Thelen, Krailling, DE;

Andre Ziegler, Laeufelfingen, CH;

Manuel Dietrich, Schongau, DE;

Ulrich Schotten, Aachen, DE;

Vinzent Rolny, Munich, DE;

Assignees:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Universiteit Maastricht, LK Maastricht, NL;

Academisch Ziekenhuis Maastricht, HX Maastricht, NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); A61B 5/318 (2021.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61B 5/318 (2021.01); G01N 2333/4712 (2013.01); G01N 2333/58 (2013.01); G01N 2800/2871 (2013.01); G01N 2800/325 (2013.01); G01N 2800/326 (2013.01);
Abstract

Disclosed is a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of ESM-1 in a sample from the subject, and comparing the amount of ESM-1 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, a method for diagnosing heart failure and/or at least one structural or functional abnormality of the heart associated with heart failure is disclosed.


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