The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2025
Filed:
Oct. 25, 2021
Mary Hitchcock Memorial Hospital, for Itself and on Behalf of Dartmouth-hitchcock Clinic, Lebanon, NH (US);
John B. Weaver, Hanover, NH (US);
Abstract
This invention provides a system and method for use of MSB with respect to nanoparticles to non-invasively so as to detect certain conditions, such as viral infection and immunological responses thereto. The system and method employs MSB, for example to detect and quantify antibody-specific NP aggregation to measure the concentration of molecular biomarkers in a wide variety of environments. The system and method can effectively differentiate antibody-specific aggregation from viscosity and temperature, which vary naturally in many environments we wish to explore. Advantageously, the system and method can provide a wide range of potential applications including, but not limited to, in vivo monitoring of immunotherapy efficacy, surgical site infection surveillance, chronic surgical pain monitoring and testing for contagions, which can be performed rapidly and at minimal cost in the field using (e.g.) unprocessed body fluid samples (blood, saliva, mucus and/or urine).