The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2025
Filed:
May. 02, 2019
Applicant:
Medizinische Hochschule Hannover, Hannover, DE;
Inventors:
Rainer Blasczyk, Isernhagen, DE;
Constanca Ferreira De Figueiredo, Neustadt am Rubenberge, DE;
Assignee:
Medizinische Hochschule Hannover, Hannover, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/078 (2010.01); A61K 35/19 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0644 (2013.01); A61K 35/19 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/155 (2013.01); C12N 2501/165 (2013.01); C12N 2501/2303 (2013.01); C12N 2506/45 (2013.01); C12N 2531/00 (2013.01); C12N 2533/30 (2013.01); C12N 2533/52 (2013.01);
Abstract
An in vitro process for producing megakaryocytes, and optionally platelets from the megakaryocytes, including the steps of cultivating stem cells, e.g. induced pluripotent stem cells, to generate aggregated pluripotent stem cells, preferably cultivating the aggregates in suspension in medium, inducing differentiation in these aggregates, and isolating megakaryocytes from the culture medium.