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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12479883 B1

PDFFull Text
Date of Patent:
Nov. 25, 2025

Filed:

Nov. 02, 2021

Methods of reducing the enzymatic hydrolysis activity rate in a composition obtained from a purification platform

Applicants:

Genentech, Inc., South San Francisco, CA (US);

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Michael Leiss, Schlehdorf, DE;

Christian Meyer, Starnberg, DE;

Alexandra Thomas Morris, Pacifica, CA (US);

Bernhard Spensberger, Eberfing, DE;

Yinges Yigzaw, San Ramon, CA (US);

Franziska Edelmann, Wolfratshausen, DE;

Roberto Falkenstein, Munich, DE;

Tobias Graf, Penzberg, DE;

Jie Gu, Thousand Oaks, CA (US);

Jeevan Prabhakar, San Francisco, CA (US);

Assignees:

Genentech, Inc., South San Francisco, CA (US);

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Kathryn Elizabeth Limbaugh

Int. Cl.
CPC ...
C07K 1/22 (2006.01); A61K 39/395 (2006.01); B01D 15/32 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01); B01D 39/16 (2006.01); B01D 39/20 (2006.01); B01D 61/14 (2006.01); C07K 1/16 (2006.01); C07K 1/20 (2006.01); C07K 1/34 (2006.01); C07K 1/36 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); A61K 39/39591 (2013.01); B01D 15/327 (2013.01); B01D 15/362 (2013.01); B01D 15/3809 (2013.01); B01D 15/3847 (2013.01); B01D 39/1623 (2013.01); B01D 39/2068 (2013.01); B01D 61/145 (2013.01); C07K 1/165 (2013.01); C07K 1/20 (2013.01); C07K 1/34 (2013.01); C07K 1/36 (2013.01); B01D 61/147 (2013.01); B01D 2239/0618 (2013.01); B01D 2315/16 (2013.01);
Abstract

The present disclosure provides purification platforms comprising a depth filter step and/or a hydrophobic interaction chromatography (HIC) step. Also disclosed herein are methods of using the purification platforms described herein and compositions obtained therefrom, such as pharmaceutical compositions.

Find Patent Forward Citations

Leiss, Michael. (2025). Methods of reducing the enzymatic hydrolysis activity rate in a composition obtained from a purification platform (U.S. Patent No. 12479883). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12479883

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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