The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Sep. 03, 2020
Applicant:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong Shanghai, CN;

Inventors:

Wenhu Duan, Pudong Shanghai, CN;

Meiyu Geng, Pudong Shanghai, CN;

Hefeng Zhang, Pudong Shanghai, CN;

Jian Ding, Pudong Shanghai, CN;

Jing Ai, Pudong Shanghai, CN;

Xia Peng, Pudong Shanghai, CN;

Yinchun Ji, Pudong Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07F 7/08 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07F 7/0832 (2013.01);
Abstract

A compound having Axl and c-Met kinase inhibitory activity, a preparation method therefor and an application thereof are provided. Specifically, provided herein are a compound having the structure represented by formula (I), a preparation method therefor and an application thereof in the preparation of a medication for the treatment and/or prevention of tumor-associated diseases and/or kinase-related diseases.


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